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NYT on pharmacological advances in addiction treatment

An Anti-Addiction Pill? – New York Times Lots of interesting stuff here on new treatments for addiction, including: A methadone (heroin-substitute) replacement called buprenorphine with less dependency...

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Time for neuroscientists to speak up?

Recently, I was pointed to this article in the WSJ (“A Pentagon Agency Is Looking at Brains — And Raising Eyebrows“) by Sharon Begley. It touches on some noninvasive recording techniques for assessing...

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If dopamine fails, try glutamate

Happy Labor Day (US)! Topping the NYT most popular articles list right now is an interesting article about a new schizophrenia treatment that targets certain glutamate receptors unlike previous...

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CB1 antagonist seems to contribute to depression

I didn’t notice this before, but in a study of about 4000 subjects, people who took Rimonabant (marketed as Acomplia), a selective antagonist of the cannabinoid type 1 receptor (CB1), apparently had a...

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Count of orphan G protein-coupled receptors

The relatively recently discovered cannabinoid receptors has me wondering how many other neuroreceptors may be left to discover. One way to estimate the number of these is to screen the genome and look...

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The truth about TTX!

If the Fish Liver Can’t Kill, Is It Really a Delicacy? [NYT, login] Amazing. It looks like TTX (tetrodotoxin, a potent voltage-gated sodium channel blocker well-known to electrophysiologists) is not...

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PBS: Not so neuroscience-savvy

Salon has an interesting piece condemning a recent PBS show purportedly on Alzheimer’s treatment but really more of a sketchy informercial. The program concerns a neurologist with tenuous ties to UC...

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Putative (unpleasant) psychedelic effects of anti-smoking drug Varenicline

http://en.wikipedia.org/wiki/Varenicline “Varenicline is a partial agonist of the ?4?2 subtype of the nicotinic acetylcholine receptor.” — this is apparently the subtype that nicotine acts on in the...

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Broad PsychHTS brings chemical biology to neuroscience

There’s a nice editorial in Nature Neuroscience about the Broad Institute’s PsychHTS initiative. The initiative invites scientists from outside the Broad to suggest new high-throughput screens that the...

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Frontiers in Neuroscience Journal

The journal, Frontiers in Neuroscience, edited by Idan Segev, has made it Volume 3, issue 1.  Launching last year at the Society for Neuroscience conference, its probably the newest...

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